International Journal of Applied Science and Engineering
Published by Chaoyang University of Technology

Chia-Ling Lien and Chi-Tung Hsu1

Department of applied Chemistry, Chaoyang University of Technology, Wufong, Taichung County 41349, Taiwan, R.O.C.


 

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ABSTRACT


The synthesis of new derivatives 2 of α-hydrazino-(disubstituted)- alkylphosphonic acids by the Lewis acid mediated addition of dialkylphosphite to hydrazones, derived from benzoylhydrazine and aliphatic ketones, is described. Reactions were successfully and catalytically promoted by BF3 etherate under mild condition in methylene chloride at room temperature.


Keywords: Lewis acid; Nucleophilic addition; dialkylphosphite; α-hydrazinoalkylphosphonic acids; ketone hydrazones; benzoic acid hydrazides.


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ARTICLE INFORMATION




Accepted: 2008-05-08
Publication Date: 2008-04-01


Cite this article:

Lien, C.-L., Hsu, C.-T. 2008. Lewis Acid-catalyzed nucleophilic addition of dialkylphosphite to hydrazones derived from benzoylhydrazine and aliphatic ketones. International Journal of Applied Science and Engineering, 6, 11–17.https://doi.org/10.6703/IJASE.2008.6(1).11


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