International Journal of Applied Science and Engineering
Published by Chaoyang University of Technology

Neerja Tewaria, Hema Menghanib, P. D. Hamrapurkarb, Tukaram Manea, Ashish Suthara*, and Vijay Singh Chauhana

a Piramal Life Sciences limited, 1, Nirlon Complex, Off. Western Express Highway, Goregaon (East), Mumbai – 400 063. Maharashtra, India
b Pharmaceutical Analysis, Principal K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaoankar Marg, Cuffe Parade, Mumbai 400 005. India.


 

Download Citation: |
Download PDF



Keywords: Hypericum perforatum; St. John’s Wort; Pharmaceutical analysis; Hyperforin


Share this article with your colleagues

 


REFERENCES


  1. [1] Linde, K., Ramiresz, G., Mulrow, C. D., Pauls, A., Weidenhammer, W., and Melchart, D. 1996. St. John’s Wort for depression-an overview and meta analysis of randomized clinical trials. Br. Med. J. 313: 253-258.

  2. [2] Volz, H. P. 1997. Controlled clinical trials of hypericum extracts in depressed patients--an overview. Pharmacopsychiatry. 30 (Suppl. 2): 72-76.

  3. [3] Gaster, B., and Holroyd, J. 2000. St John's Wort for depression: a systematic review. Archives Internal Medicine. 160, 2: 152-156.

  4. [4] Bombardelli, E., and Morazzoni, P. 1995. Hypericum perforatum. Fitoterapia. 66: 43.

  5. [5] Erdelmeier, C. A. 1998. Hyperforin, possibly the major non-nitrogenous secondary metabolite of Hypericum perforatum L.  Pharmacopsychiatry. 31 (Suppl. 1): 2-6.

  6. [6] Müller, W. E. 2003. Current St John's Wort research from mode of action to clinical efficacy. Pharmacological Research. 47, 2: 101-109.

  7. [7] Nöldner, M., and Schötz, K. 2002. Rutin is essential for the antidepressant activity of Hypericum perforatum extracts in the forced swimming test. Planta Medica. 68 (7): 577-580.

  8. [8] Butterweck, V. Petereit, F.  Winterhoff, H., and Nahrstedt, A. 1998. Solubilized hypericin and pseudohypericin from Hypericum perforatum exert antidepressant activity in the forced swimming test. Planta Medica. 64, 4: 291-294.

  9. [9] Holzl, J., and Ostrowski, E. 1987. HPLC analysis of the constituents and the variety in populations. Dtsch. Apoth. Ztg. 127, 23: 1227-1230.

  10. [10] Brolis, M. Gabetta, G. Fuzatti, N. Pace, R.  Panzeri, F., and Peterlongo, F. 1998. Identification by high performance liquid chromatography-diode array detection-mass spectrometry and quantification by high performance liquid chromatography-UV absorbance detection of active constituents of Hypericum perforatum. Journal of Chromatography A. 825, Issue 1: 9-16.

  11. [11] Liu, F. F. Ang, C. Y. W., and Springer, D. Optimization of extraction conditions for active components in Hypericum perforatum using response surface methodology. Journal of Agricultural and Food Chemistry. 48, 8: 3364-3371.

  12. [12] Liu, F. F. Ang, C. Y. W. Heinze, T. M. Rankin, J. D. Beger, R. D. Freemen, J. P., and Lay Jr., J. O. 2000. Evaluation of major active components in St. John’s Wort dietary supplements by high performance liquid chromatography with photodiode array detection and electrospray mass spectrometric confirmation. Journal of Chromatography A Issue 1-2: 85-92.

  13. [13] Rückert, U., Likussar, W., and Michelitsch, A. 2007. Simultaneous determination of total hypericin and hyperforin in St. John’s Wort extracts by HPLC with electrochemical detection. Phytochemical Analysis. 18: 204-208.

  14. [14] Rückert, U., Eggenreich, K., Wintersteiger, R., Wurglics, M., Likussar, W., and Michelitsch, A. 2004. Development of a high-performance liquid chromatographic method with electrochemical detection for the determination of hyperforin, Journal of Chromatography A. 1041: 181–185.

  15. [15] De los Reyes, G. C., and Koda, R, T. 2001. Development of a simple, rapid and reproducible HPLC assay for the simultaneous determination of hypericins and stabilized hyperforin in commercial St. John’s Wort preparations, Journal of Pharmaceutical and Biomedical Analysis. 26: 959-965.

  16. [16] Rozio, M., Fracasso, C., Riva, A., Morazzoni, P., and Caccia, S. 2005. High-performance liquid chromatography measurement of hyperforin and its reduced derivatives in rodent plasma. Journal of Chromatography B, Analyti- cal Technologies in the Biomedical and Life Sciences. 816: 21-27.

  17. [17] Gioti, E. M., Skalkos, D. C., Fiamegos, Y. C., and Stalidas, C. D. 2005. Single-drop liquid-phase microextraction for the determination of hypericin, pseudohypericin and hyperforin in biological fluids by high performance liquid chromatography. Journal of Chromatography A. 1093: 1-10.

  18. [18] Draves, A. H., and Walker, S. E. 2000. Determination of hypericin and pseudohypericin in pharmaceutical preparations by liquid chromatography with florescence detection. Journal of Chromatography B Biomed. Sci. Appl. 749, 1: 57-66.

  19. [19] Maisenbacher, P., and Kovar, K. A. 1992. Analysis and stability of Hyperici oleum. Planta Medica. 58, 4: 351-354.

  20. [20] Orth, H. C. J., Rentel, C., and Schmidt, P. C. 1999. Isolation, purity analysis and stability of hyperforin as a standard material from Hypericum perforatum Journal of Pharmacy and Phamacology.51: 193-200.

  21. [21] Verotta, L., Appendino, G., Belloro, E., Jakupovic, J., and Bombardelli, E. 1999. Furohyperforin, a prenylated phloroglucinol from St. John's Wort (Hypericum perforatum) Journal of Natural Products. 62, 5: 770-772.

  22. [22] Verotta, L., Appendino, G., Jakupovic, J., and Bombardelli, E. 2000. Hyperforin analogues from St. John's Wort (Hypericum perforatum). Journal of Natural Products. 63, 3: 412-415.

  23. [23] Trifunovic, S., Vajs, V., Macura, S., Juranic, N., Djarmati, Z., Jankov, R., and Milosavljevic, S. 1998. Oxidation products of hyperforin from Hypericum perforatum. Phytochemistry. 49, 5: 1305-1310.


ARTICLE INFORMATION




Accepted: 2008-06-24
Available Online: 2008-04-01


Cite this article:

Tewari, N., Menghani, H., Hamrapurkar, P.D., Mane, T.,  Suthar, A., Chauhan, V.S. 2008. Development of a High-Performance liquid chromatographic method for the quantitative determination of hyperforin. International Journal of Applied Science and Engineering, 6, 39–46.https://doi.org/10.6703/IJASE.2008.6(1).39


We use cookies on this website to improve your user experience. By using this site you agree to its use of cookies.