International Journal of Applied Science and Engineering
Published by Chaoyang University of Technology

Katta Vijaykumar1, Papolu B. Murthy1, Sukala Kannababu1, B. Syamasundar2,and Gottumukkala V. Subbaraju1*

1 Laila Research Centre, Unit I, Phase III, Jawahar Autonagar, Vijayawada – 520 007, India
2 Department of Chemistry, Acharya Nagarjuna University, Nagarjuna Nagar–522 510,India


 


 

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ABSTRACT


Lagerstroemia speciosa extracts and their active ingredient, corosolic acid exhibitssignificant anti-diabetic activity in humans. A reliable and reproducible high performance liquidchromatography (HPLC) and high performance thin layer chromatography (HPTLC) methodshave been developed for the quantitative determination of corosolic acid in Lagerstroemia speciosaleaves and extracts. The methods developed have demonstrated good precision and recoverywith % RSD less than 2%. The contents of corosolic acid determined by HPLC and HPTLCmethods are in good agreement. The methods developed have also been employed for quantitativedetermination of corosolic acid in Lagerstroemia speciosa leaves and extracts. HPLCmethod has been found suitable for the quantitative determination of corosolic acid in dosageforms also.


Keywords: Corosolic acid, Lagerstroemia speciosa, dosage forms, HPLC, HPTLC


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REFERENCES


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ARTICLE INFORMATION




Accepted: 2006-09-08
Available Online: 2006-09-01


Cite this article:

Vijaykumar, K., Murthy, P.-B., Kannababu, S., Syamasundar, B., Subbaraju, G.-V. 2006. Quantitative determination of corosolic acid in lagerstroemia speciosa leaves, extracts and dosage Forms. International Journal of Applied Science and Engineering, 4, 103–114. https://doi.org/10.6703/IJASE.2006.4(2).103


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