Vernonia amygdalina extract induces apoptosis and inhibits epithelial-mesenchymal transition in Hep 3B cells through the inhibition of PI3k/Akt signaling pathway

Chen-Chu Lai¹, Xinran Zhou², Hao-Kuang Wang^3,4, Ying-Chao Lin^5,6,7, Hui-Yi Lin⁸, Tzong-Der Way^2,9, Bing-Lan Liu^1*

¹ Department of Applied Chemistry, Chaoyang University of Technology, Taichung, Taiwan, ROC

² Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC

³ Department of Neurosurgery, E-Da Hospital/I-Shou University, Kaohsiung, Taiwan, ROC

⁴ School of Medicine, I-Shou University, Kaohsiung, Taiwan, ROC

⁵ Division of Neurosurgery, Buddhist Tzu Chi General Hospital, Taichung Branch, Taiwan

⁶ School of Medicine, Tzu Chi University, Hualien, Taiwan, ROC

⁷ Department of Medical Imaging and Radiological Science, Central Taiwan University of Science and Technology, Taichung, Taiwan, ROC

⁸ School of Pharmacy, College of Medicine, College of Pharmacy, China Medical University, Taichung, Taiwan, ROC

⁹ Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan, ROC.

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